Figure 5 shows the fraction of compromised and non compromised patients having i
ID: 178478 • Letter: F
Question
Figure 5 shows the fraction of compromised and non compromised patients having infections with diffrent chromosomal virulence factors. explain the graph, and suggest the pattern based on your knowledge of host defense?
60 T 50 E 40 30 20 10 Number of Chromosomal Vlrutenc. Factors Present in Strain (P fimbria., Aerobactin, or Homolysin) FIG. 5. Distribution of combined CVFs in strains from compro- mised and noncompromised patients. Patients were sorted by the presence or absence of compromising medical and urological con- ditions and further sorted by the number of cVF determinants present in the strains isolated from them (as described in the legend to Fig. 4). The fraction of each group of patients (compromised ln 47 or noncompromised I.)In 11D associated with each cvF category (0 to 3)Explanation / Answer
In the above graph,compromised patients out of 47 patients around 32% of the patients are exposed to first chromosomal virulaence factor, followed by exposing to second virulaence factor to 26% and exposed to third virulaence factor to aroung 28%.
Where as in the case of non compromised patients out of 11 patients they are exposed to first virulaence factor to 18%, second virulaence factor to 28% and third virulaence factor to around 58%.
Based on this data in the lines of host defence in compromised patients to the second virulaence factor they are showing defence activity when compared to the other two virulaence factors. For the non compromised patients the host defence is more to the first virulaence factor.
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