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Fill in the blanks to complete the narrative with choosing the appropriate word.

ID: 178188 • Letter: F

Question

Fill in the blanks to complete the narrative with choosing the appropriate word. The History of DNA as Genetic Material:

In the late 1800s scientists where convinced that (5) contained genetic material. However, there was much debate about whether DNA or Protein was responsible for being genetic material. Chromosomes are comprised of (6) which is a DNA+protein complex, specifically (7) as the protein portion. In 1920 (8) conducted an experiment. He used (9) rough and smooth strains. Rough strain injected into a mouse, the mouse (10). Smooth strain injected into the mouse, the mouse (11). Heat killed smooth strain injected into the mouse, the mouse (12). However when Heat-killed smooth strain was mixed with the rough strain and injected into the mouse, the mouse (13). This experiment baffled the researcher, but this was the first hint that (14) was the genetic material. The traits and characteristics of the smooth strain that made it virulent were transferred to the rough strain through a process called (15). In 1940, (16) expanded on the previous research. The DNA from the smooth bacteria was (17). Five samples were created. The (18) test tube contained only the Rough bacteria, which would not grow on the petri dishes. The second test tube contained smooth DNA + rough bacteria, (19) occurred and once plated on the petri dishes colonies grew. In the third test tube, smooth DNA + rough bacteria+ (20) added and no colonies grew on the petri dish. In the fourth test tube smooth DNA + rough bacteria+ (21) knocking out ribonucleic acid function was added and colonies grew on the petri dish. In the fifth test tube smooth DNA + rough bacteria+ (22) thus preventing protein production and colonies grew on the petri dish. This experiment shows that in test tube 3, no colonies grew because smooth strain (23) was blocked/destroyed by (24). Thus (25) is the transforming principle .

Answer choices #1- 21 m be used more than once RNA AC Chromatin DNA Histone DNAse Information AE Griffith RNAse BC Avery, McLeod, Protease BD McCarty AB Chromosomes BE Hershey & Chase CE DE ABC ABD ABE Replicated Transmission Lived Died Variation Purified BcD Transformation BCE S. pneumoniae Control CDE

Explanation / Answer

5) Chromosomes

6) chromatin

7) histone

8)Griffith

9) S.pneumonieae

10)lived

11)died

12)lived

13)died

14)DNA

15)transformation

16)Avery,Mcleod,Mcarthy

17)purified

18)control

19)transformation

20) DNAase

21) RNAase

22) protease

23) replication

24)

25) DNA

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