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you will be asked to consider 3 viral diseases for which there is currently not

ID: 177841 • Letter: Y

Question

you will be asked to consider 3 viral diseases for which there is currently not a human vaccine. They are as follows, with a link to the CDC website that will provide you with an appropriate background regarding each disease.

1.) Chickungunya:  https://www.cdc.gov/chikungunya/ (Links to an external site.)

2.) MERS:  http://www.cdc.gov/coronavirus/mers/index.html (Links to an external site.)

3.) Zika:  https://www.cdc.gov/zika/ (Links to an external site.)

Your final will be in two parts.

Part 1: As the new director of the CDC, you are empowered to petition congress and the president for funds to develop a vaccination program for any of these viral diseases, but you realize that you will likely only get one. So you will chose the one that you think will make the greatest positive impact on the health and well-being of the citizens of the United States.

section A: Which one do you choose? Justify your choice by comparing the pros and cons for each of the three viruses (i.e. don't just tell me why your choice is the best - also tell me why the others are not as good of a choice.

section B: For the one you chose, you will then fund one major strategy for development (attenuated, inactivated, subunit, or DNA). Which strategy do you choose? Justify your choice by comparing the pros and cons for each of the four strategies as they might pertain to your chosen virus. Be sure you cite the advantages and disadvantages of each approach, and why you think overall your choice is the best one.

Explanation / Answer

I would choose Zika virus that is caused due to mosquito bites in the day and nignt. Apart from this mosquitoes that spread Zika virus also spread dengue and chikungunya viruses. Middle East Respiratory Syndrome (MERS) is an illness caused by a virus called Middle East Respiratory Syndrome . Most of the cases of MERS is through  travel to, or residence in, countries in and near the Arabian Peninsula.

Vaccine should induce strong, efficient and long lasting immune response. It is recommended by WHO to develop inactivated vaccines and other non-live vaccines. This is because they are not active forms and will not lead to infection. DNA vaccines or peptide vaccine can also be develop. These will be easy to manufacture compared to inactivated vaccines as improper inactivation will lead to infection with zika virus