Answer True or False to the following... 1. An excessive level of gluccocorticoi
ID: 176319 • Letter: A
Question
Answer True or False to the following...
1. An excessive level of gluccocorticoids may cause a rearrangement of fat culminating in the deposition of fat at the base of the neck and around the cheeks; this is characteristic of Addison's disease.
2. The surface of the skin is fairly inhospitable to most organisms, an exception being Staphylococcus.
3. The constant monitoring of normal tissues by Natural Killer cells is called "immunological surveillance".
4. Kupffer cells are macrophages that wander throughout the body.
5. The many layers of squamous cells comprising the epidermis provide a chemical barrier against infection.
6. Anything that stimulates beta-adrenergic receptors on cardiac muscle would cause a decrease in heart rate.
7. If the thymus failed to produce thymic hormones, B lymphocytes would not develope properly.
8. All cells and tissues in the body contain antigens that normally fail to stimulate an immune respone, the immune system is said to exhibit "tolerance" toward such antigens.
9. A patient with a golden-brown tan in the winter (no tanning bed or fancy vacations or bad makeup job), polyuria, hyperglycemia, hypotension and polydypsia may be suffering from Addison's disease.
10. Complement proteins are produced by the liver and cause cell lysis to cells that are deemed by the immune system to be "non-self" or foreign.
11. Glycosylated hemoglobin, or HgA1C is a screening test for diabetes.
12. Interferons are one of the greatest chemical agents against bacteria.
13. IgG antibodies can cross the placenta, and in the case of hemolytic disease of the newborn, IgG's cross the placenta and attack fetal Rh negative red blood cells.
14. Iodine is required in order for the thyroid gland to produce thyroxin.
15. You bring your child in to the physician and they inject him or her with three vaccines.
16. Immunity due to vaccination would be characterized as active, natural.
17. IgA may be found in tears and saliva.
18. A Type I Hypersensitivity reaction involves Cytotoxic T cells and is often delayed.
19. Thalassemias are genetic diseases that involve insufficient hemoglobin production in those of European Jewish ancestry.
Explanation / Answer
1. False. Addison's disease characterized by weight loss, muscle weakness, fatigue, low blood pressure and darkening of the skin in both exposed and non-exposed parts of the body. Deposition of fat at the base of neck and around the cheeks are the characteristics of Cushing's syndrome.
2. True. Staphylococcus produce a biofilm which protects it from the antibiotics and also from the skin immunity.
3. True. NK celss demolished tumor through perforin and granzyme which are important for immune surveillance.
4. False. Kupffer cells are specialized macrophages located in liver and microglia of the brain.
5. False. Epidermis provides a physical barrier against infection.
6. False. beta-adregenic receptors increase cardiac output by increasing heart rate.
7. False. A lack of thymic hormones would drastically reduce the population of T lymphocytes by preventing their differentiation from lymphoid stem cells.
8. False. If cells and tissues contain antigens that normally fail to stimulate an immune response, it is known as autoimmune response.
9. True. Addison's disease characterized by weight loss, muscle weakness, fatigue, low blood pressure and darkening of the skin in both exposed and non-exposed parts of the body.
10. True. Complement proteins are mainly produced by liver and they distinguish self from non-self.
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