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Question XIV. Consider each numbered statement (195-200) as a completely indepen

ID: 175305 • Letter: Q

Question

Question XIV. Consider each numbered statement (195-200) as a completely independent assertion. Using your current knowledge and basic rules of formal and informal logic, please, assess the following statements as factually correct (true) or incorrect (false):

195. The mechanisms of autoimmune diseases do not include a failure of peripheral tolerance.

196. Autoimmunity does not lead to tissue destruction.

197. Individuals who express HLA-B27 are 90 times more likely to develop the autoimmune disorder ankylosing spondylitis than individuals with a different HLA allele at this locus; this leads to the conclusion that HLA-B27 causes ankylosing spondylitis.

198. Individuals who express HLA-B27 are 90 times more likely to develop the autoimmune disorder ankylosing spondylitis than individuals with a different HLA allele at this locus; this leads to the conclusion that individuals with HLA-B27 are highly likely to develop ankylosing spondylitis.

199. Individuals who express HLA-B27 are 90 times more likely to develop the autoimmune disorder ankylosing spondylitis than individuals with a different HLA allele at this locus; this leads to the conclusion that autoimmune disorders must have genetic components.

200. Individuals who express HLA-B27 are 90 times more likely to develop the autoimmune disorder ankylosing spondylitis than individuals with a different HLA allele at this locus; this leads to the conclusion that most patients with ankylosing spondylitis express HLA-B27.

Explanation / Answer

Answers for Question XIV:

195. True

196. False

197. False ( It is not 100% proven that Individuals who express HLA-B27 suffer from ankylosing spondylitis.)

198. True ( Presence of HLA-B27 allele can only be taken as a parameter for cause of ankylosing spondylitis. )

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