Question 1) The mature erythrocyte A. uses fatty acids as the main source of ene

Question

Question 1) The mature erythrocyte A. uses fatty acids as the main source of energy. B. reduces NADP+ to NADPH largely through the hexose monophosphate shunt. C. produces bisphosphoglycerate (DPG) largely via the hexose monophosphate shunt. D. synthesizes proteins. E. contains relatively extensive endoplasmic reticulum.

Question 2) The principal source of NH4+ for glutamine synthesis in muscle is A. glutamate. B. adenosine. C. inosine. D. urea. E. carbamoyl phosphate.

Question 3) Lactate production during muscular contraction is ascribed in part to A. an overproduction of acetyl-CoA not metabolized in the Krebs cycle. B. an underproduction of acetyl-CoA for utilization in the Krebs cycle. C. temporary anaerobic state in muscle. D. overabundance of ATP produced by metabolism through the Krebs cycle.

Explanation / Answer

Question 1.B

The erythrocyte metabolism needs ATP as a source of energy and NADH and NADPH cofactors. The metabolic needs of erythrocytes are met by metabolism of glucose through three pathways glycolysis, the hexose monophosphate shunt and Rapport-Luebering glycolytic shunt.

Question 2: A

Cells get rid of excess ammonia by the reductive amination of ketoglutarate to form glutamate by glutamate dehydrogenase and the conversion of glutamate into glutamine by glutamine synthetase.The principal source of NH4+ for glutamine synthesis in muscle is glutamate.Glutamine synthetase use ATP to activate glutamate for amination to form glutamine.

QUestion 3. B. an underproduction of acetyl-CoA for utilization in the Krebs cycle.

Because pyruvate converts in Lactic acid so there is depletion in Acetyl-COA

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