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cure https://usflearn.Instructure.com/courses/11942591quizzes/1616816/take/questions/35795058 63.00AS17 Quizzes Homework 10 Homework 10 Started Mar 24 at 107am Quiz Instructions Select the best answer. You are allowed just one attempt. ONIYQUESTIONS 1-10 ARE GRADED. The remaining questions are merely for practice. Correct answerswin be avalable aner the quizis due Note due dateis Friday March 24 at 1159 pm Question 4 1 pts What role does a topoisomerase play in DNA replication? Hold single strands of DNA open Unwind doubleDNA helices Release torsional stress of supercoiled DNA Turm DNA on its axis 0 Makes helical DNA Next Quiz saved at 413am MacBook Air Questi Time Elaps Hours, S.Explanation / Answer
Answer: UNWIND DOUBLE DNA HELICES
*Topoisomerases are group of enzymes that participate in the UNDERWINDING or overwinding of DNA.
*The winding problem of DNA arises due to the intertwined nature of its DOUBLE HELICAL structure.
*During DNA Replication,DNA becomes overwound ahead of replication fork. If left unabated,this would stop the ability of DNA polymerases involved in this process to continue down the DNA strand.
*To prevent these types of topological problems caused by the double helix, Topoisomerases bind to double stranded DNA ,cut the phosphate backbone which allows the DNA to be Unwound/ Untangled.
* In simple, Topoisomerases are Isomerase enzymes that act on the topology of DNA.
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