Explain what would happen in each case below; assume that each of these proteins

Question

Explain what would happen in each case below; assume that each of these proteins is NOT a membrane protein. Write answers on the back of this paper. A. You add a signal sequence (for the ER) to the N-terminus of a normally nuclear protein. B. You change the hydrophobic amino acids in an ER signal sequence into polar amino acids. C. You change the hydrophobic amino acids in an ER signal sequence into other hydrophobic amino acids. D. You add a N-terminal ER signal sequence to the C-terminal end of a normally cytoplasmic protein.

Explanation / Answer

ans- 1- THE protein will now be transported in to the ER lumen.

2-the the altered sequence will not be recognise and protein will remain in the cytosol.

3- it will deliveredtothe ER

4-The protein will not enter ER endocytolplasmic retuculam.

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