T/F? the mutation rate (per base pair per generation) for CNVs (copy number vari
ID: 167797 • Letter: T
Question
T/F? the mutation rate (per base pair per generation) for CNVs (copy number variants) is approximately 5 times 10^-6 which is lower than the mutation rate for substitutions. Let's consider mitochondrial linked diseases. Mitochondrial diseases can be corrected with methods currently in development. Which of the following are methods that we discussed applying to mitochondrial linked diseases? (Circle all that apply) Knockout CRISPR-cas9 Pronuclear Transfer Maternal Spindle Transfer If a woman has a mitochondrial disease, what is the probability she will pass this disease on to her son? What is the probability that the son will pass the same disease on to his offspring? You are investigating one of several candidate genes in a QTL. For this gene, you find that there are a few silent substitutions in the exons and there are no missense or nonsense substitutions and no indels in the exons. There are also a few substitutions in the noncoding DNA upstream of the gene. Which of the following accurately describe this situation? (Circle all that apply) This candidate gene is not likely to contain a mutation that affects the quantitative trait being studied This candidate gene is not likely to contain a mutation that affects the function of the protein it encodes This candidate gene is not likely to contain a mutation that affects the expression level of the protein it encodes How many possible unique gamete genotypes are produced from an organism with the genotype w+ wc+ cr+ rv+ v, assuming the genes w, c, r, and v are not linked? _Explanation / Answer
Answer:
4).
w+wc+cr+r+v+v
The following genes have two types of alleles = w, c, v
Gene "r" have one type of allele= r+
2 * 2 * 1 * 2 = 8
Total 8 types of gametes are produced. Those are..
1. w+c+r+v+
2. w+c+r+v
3. w+cr+v+
4. w+cr+v
5. wc+r+v+
6. wc+r+v
7. wcr+v+
8. wcr+v
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