Thinking about the Central Dogma and its relationship to any and all concepts or

Question

Thinking about the Central Dogma and its relationship to any and all concepts or a gene, determine whether the following statements are true or false: A gene provides the information necessary for the formation of the secondary structure of a protein. Mutations in a gene might lead to a change in the tertiary structure of a protein. An allele can manifest as an alternative RNA sequence. A mutation that causes a truncated (not full length) protein might suggest a misses mutation in the nucleic acid sequence.

Explanation / Answer

option A is true.

sequence of Nucleotide decides the whether a protein will form alpha-helix or Beta-sheet.

For example- the usually alpha chain is present in the transmembrane domain of the protein which is made up of hydrophobic residues which in turn is decided by the nucleotide sequence of the gene.

Option B- True

tertiary structure is made when secondary structure arranges themselves in 3D. Domains of the tertiary structure are made up of amino acids coming from the different secondary structure. if there is any mutation in the gene which will lead to distortion of tertiary structure.

Option C true.

An allele is made up of the same gene but due to single point mutation there is change in the amino acid sequence and thus lead to change in the protein fiucntuon

Option D- missi=ense mutation is a mutation in which there is a change in single nucleotide which I will lead to change in the single amino acid in the protein sequence. Whereas a mutation that causes a truncated protein might suggest a nonsense mutation in the nucleic acid

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