Protein kinase cascades are significant because amplification can occur at each

Question

Protein kinase cascades are significant because amplification can occur at each step in the path information at the plasma membrane is communicated to the nucleus. the multiple steps allow for specificity of the process. All of the above Indicate whether each of the following descriptions better applies to a weel protein (W) or a Cdc25 protein (C). Your answer would be a four-letter string composed of letters W and C only, e.g. WWCW. (__) It is a protein kinase. (__) It activates M-Cdk complexes. (__) It is activated by M-Cdk complexes. (__) Its loss in fission yeast results in small cell size. Which of the following is more directly driven by active M-cdk? Maturation of mitosis specific proteins Chromosome duplication Nuclear envelope reassembly Inactivation of APC/C Cell cleavage Select the order that is correct for signal transduction Binding of a signal, secondary messenger released, receptor conformation altered, cellular function altered

Explanation / Answer

31. Protein kinase cascades are significant because

d) All of the above. (A protein kinase cascade is a chain of kinase enzymes that modify other proteins by phosphorylation. They transmit extracellular signals into the cell i.e. they help in cell communication. The transmitted signal is amplified at each step. Also, since it is a multi-step pathway, each step produces specific molecules i.e. specificity at each step.)

32. (W) is a protein kinase.

(W) It activates M-Cdk complexes.

(C) It is activated by M-Cdk complexes.

(W) Its loss in fission yeast results in small cell size.

33.Which of the following is more directly driven by active M-Cdk?

A) Maturation of mitosis specific proteins.

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