Link: https://www.sciencedaily.com/releases/2016/12/161215143511.htm 1. What is

Question

Link: https://www.sciencedaily.com/releases/2016/12/161215143511.htm

1. What is a cyclin-dependent kinase and how is it thought to work? (Answer not found in article – see your text book or my lecture.)

2. Why was Heinemann’s hypothesis that a metabolic oscillator might set the pace for cell division a good bet? (Hint: What does a cell need to carry out cellular work?)

3. Why was Heinemann’s choice of NADH and ATP as indicators of the metabolic oscillators an appropriate choice?

4. Under what conditions are the metabolic and cell-cycle oscillators coupled? When are they uncoupled?

Explanation / Answer

1. Cyclin dependent kinase regulate cell cycle.

There are four types of cyclin proteins found in humans. They are- G1 cyclin, G1/S cyclin, S cyclin and M cyclin.

The level of a cyclin increases at the stage of the cell cycle when it is required. Cyclin dependent kinase binds to a cyclin and becomes active. After this,the kinase targets specific proteins by attaching a phosphate group to it. These proteins are targeted according to the cell cycle period controlled by the concerned cyclin.

Related Questions

Navigate

• Browse (All)
• Browse L
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.