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How can you be a \"carrier\" of sickle cell disease? If you are infected by some

ID: 162102 • Letter: H

Question

How can you be a "carrier" of sickle cell disease? If you are infected by someone who has sickle cell disease, but your immune system mostly fights it off, you will be a carrier. If you inherit the sickle cell allele from both your parents, you will be a carrier. If you inherit the sickle cell allele from one of your parents, you will be a carrier. If you come into contact with someone with sickle cell disease but you are not actually infected, you will be a carrier. What did Dr. Allison discover about the relationship between the sickle cell trait and malaria? Malaria causes the sickle cell trait to develop. The sickle-cell trait causes malaria. People with malaria are resistant to the sickle cell disease. People with the sickle cell trait are resistant to malaria. Mendel found that tall pea plants are genetically dominant over short pea plants. This means that Tall pea plants produce many more peas than short pea plants. Even if a pea plant contains only the genes for shortness, it still might be tall. A tall pea plant will overpower and kill off a short pea plant next to it. If a plant contains a tall and a short gene, the plant will be tall. Traits are sometimes said to "skip a generation." How does this happen according to Mendel's If an allele determining a trait is dominant, recessive alleles from cither parent can mask it, like when Mendel's first generation of flowers from a white and purple parent where all purple. If an allele determining a trait is recessive, dominant alleles from either parent can mask it, like when Mendel's first generation of flowers from a white and purple parent were all purple. If an allele determining a trait is recessive, it sometimes just doesn't show up, regardless of what traits the parents have, like when Mendel only got purple flowers in the first generation. Sometimes mutations allow a new trait to mask a recessive trait for one generation. Mendel found this to be the case in his second generation where he got both purple and white flowers.

Explanation / Answer

1. How can you be a carrier of sickle cell disease?

Answer: (b) If you inherit the sickle cell allele from both your parents, you will be a carrier.

Sickle cell disease is inherited in an autosomal recessive pattern. For a child to be diagnosed with the disease, both parents are affected equally and must carry a defected gene. Two sickle cell genes give SCD where as one sickle cell gene gives sickle cell trait.

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