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Two women have benign pituitary tumors. Andrea has lost weight and complains of

ID: 15155 • Letter: T

Question

Two women have benign pituitary tumors. Andrea has lost weight and complains of being hot all the time; she presents as thin and nervous, with tachycardia and exophthalmos.
Bethany has gained weight in her abdomen and presents with a round face and thin arms and legs with stretch marks; she says that at her last checkup her doctor told her she was prediabetic.
a. What hormones are being secreted by the pituitary tumors in these patients? What is your evidence for each?
b. Which condition does Andrea most likely have?
c. Bethany?
d. Explain the mechanism for each of Andrea’s symptoms as it relates to her condition.
e. Do the same with Bethany.

Explanation / Answer

Thyroid Stimulating Hormone (TSH) Growth Hormone (GH) Melanocyte-Stimulating Hormone (MSH) Prolactin (PRL) evidence :- pituitary tumor is an abnormal growth of pituitary cells. Pituitary tumors can either be nonfunctional (that is they do not secrete hormones) or produce specific hormones, such as prolactin (causing infertility, decreased libido, and osteoporosis), growth hormone (causing acromegaly), ACTH (causing Cushing's), TSH (causing hypothyroidism), or be nonfunctional (that is they do not produce hormones) An imbalance occurs, leading to more than a dozen disorders of the endocrine system. Deficiency of thyroid hormone, adrenal cortical hormone (cortisol) or antidiuretic hormone (vasopressin) is rapidly life-threatening. In patients with abnormalities of the other hormones, quality of life is significantly compromised. symptoms:- These hormones have dramatic effects on metabolism, blood pressure, sexuality, reproduction, and other vital body functions. In addition, the pituitary gland produces growth hormone for normal development of height and prolactin for milk production.