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After back-crossing, the resulting animal (F1) is heterozygous for the m allele.

ID: 151448 • Letter: A

Question

After back-crossing, the resulting animal (F1) is heterozygous for the m allele. If the mutation m is dominant, both homozygous (m/m) and heterozygous (m/+) F2 animals will produce the M phenotype. How can you make a homozygous mutant animal in this context? Select all that apply.

Cross the F2 M phenotype hermaphrodites with F2 M phenotype males. All M phenotype individuals in the next generation will be m/m

Cross the F2 M phenotype hermaphrodites with F1 males. All M phenotype individuals in the next generation will be m/m

Self the F2 M phenotype hermaphrodites. m/m individuals will produce ¼ m/m offspring with the M phenotype

Self the F2 M phenotype hermaphrodites. m/m individuals will produce only m/m offspring with the M phenotype

Self the F2 M phenotype hermaphrodites. m/+ individuals will produce ¼ wild-type offpring.

Additional back-crosses to wild-type will increase the likelihood of obtaining m/m individuals with the M phenotype from those crosses.

Cross the F2 M phenotype hermaphrodites with F2 M phenotype males. All M phenotype individuals in the next generation will be m/m

Cross the F2 M phenotype hermaphrodites with F1 males. All M phenotype individuals in the next generation will be m/m

Self the F2 M phenotype hermaphrodites. m/m individuals will produce ¼ m/m offspring with the M phenotype

Self the F2 M phenotype hermaphrodites. m/m individuals will produce only m/m offspring with the M phenotype

Self the F2 M phenotype hermaphrodites. m/+ individuals will produce ¼ wild-type offpring.

Additional back-crosses to wild-type will increase the likelihood of obtaining m/m individuals with the M phenotype from those crosses.

Explanation / Answer

Additional back-crosses to wild-type will increase the likelihood of obtaining m/m individuals with the M phenotype from those crosses.

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