13. When multiple cytokines have the same effect on the same cell, by definition

Question

13. When multiple cytokines have the same effect on the same cell, by definition they have: A) pleiotropy B) redundancy C) synergism D) antagonism 14. Which of the following cytokines has been found in the synovial fluid (knee fluid) of patients previously diagnosed with Rheumatoid Arthritis? A) TGFB B) TNFa C) IL-2 D) IL-5 15. Which of the following represents C3 convertase? A) C4b2a B) C3bBbP C) Ciqrs D) A and B E) Aand C Which of the following is important in the induction of the immune response? A) B) C) D) 16. Amount of antigen Timing of the injections Route of the injections All of the above are important 17. Components of bacterial cell surface itself will activate complement via which pathway(s)? A) classical B) alternative C) MBL D) two of these E) all of these 18. The C5 convertase of the alternative pathway of complement activation is: A) C4b B) C4b2a C) C4b2a3b D) C3bBb3bP

Explanation / Answer

13 . C) Redundancy - a mechanism by which different cytokinesis have the same effect on the cell.

14 .b) TNF alpha . There are two major cytokines in rheumatoid arthritis - IL-1 and TNF alpha .

15 . D) A and B . C3 convertase produced in the alternative pathway (C3bBb) or the classical and lectin pathways (C4bC2a).

16 . All of the above are true . All of these factors are important in induction of immune system .

17.B) Alternative . The activation of the complement system by the peptidoglycan of bacterial cell wall is an example of alternative activation .

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