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1. The majority of DNA viral genomes are replicated using None of the following

ID: 148893 • Letter: 1

Question

1. The majority of DNA viral genomes are replicated using

None of the following answers

Host-encoded DNA-dependent DNA polymerase

Virally encoded RNA-dependent DNA polymerase

Virally encoded RNA-dependent RNA polymerase

Virally encoded DNA-dependent DNA polymerase

2.Which of the following does not play a role in virus entry?

fusion of viral and plasma membrane

microtubule-mediated transport

clathrin-mediated endocytosis

lysosomes

diffusion of virus particles into the cytoplasm

None of the following answers

Host-encoded DNA-dependent DNA polymerase

Virally encoded RNA-dependent DNA polymerase

Virally encoded RNA-dependent RNA polymerase

Virally encoded DNA-dependent DNA polymerase

Explanation / Answer

1. DNA viruses may replicate their genome using host or viral DNA-dependent DNA polymerase.

Few viruses like Parvovirus and Papovaviral utilize host cellular DNA-dependent DNA polymerase.

Most viruses use their own or virally encoded DNA-dependent DNA polymerase.

Answer: Virally encoded DNA-dependent DNA polymerase.

2. Viral particle either binds to cell surface receptors, or fuse to cell membrane or endosomes. Virus cannot directly enter through membrane into cytoplasm by diffusion.

Answer: diffusion of virus particles into the cytoplasm.