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The Big Picture 1 ungi are fascinating microbes th at seem to enjoy masquerading

ID: 148453 • Letter: T

Question

The Big Picture 1 ungi are fascinating microbes th at seem to enjoy masquerading as plants. The majority of infections they cause are in individuals who are immunocompromised and unable to defend against pathogens. In some cases, fungi find ways to cause infection in healthy persons. During your examination of the topics in this chapter, consider the following 1. Which infections are potentially life-threatening to those without immune defenses? 2. Which fungal infections are opportunistic in healthy individuals who share public spaces? 3. In which industry are technicians required to prove licensure to operate? 4. What type of pathogenic mutation has made treating fungal infections more difficult?

Explanation / Answer

Fungal pathogens are opportunistic. They do not cause disease unless there is a disturbance in immune homeostasis. Infections such as desert rheumatism, pneumonia, and invasive pulmonary aspergillosis are all life threatening to those without immune defences.

Opportunistic fungal infections include coccidiodomycosis infections and dermatophytosis.

Technicians working in medical facilities, hospitals, schools, cafeterias and public open spaces are required to prove licensure to operate.

Fungi have the ability to quickly pass along infectious genes via “horizontal” gene transfer. Also, since fungi and animals are closely related it is difficult to find drugs that specifically act on fungi.