T/F e) If the DNA, RNA and protein products of two cells are identical, they can
ID: 147479 • Letter: T
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T/F e) If the DNA, RNA and protein products of two cells are identical, they can still respond differently to an extracellular ligand binding a receptor on their surface. T/F f) All growth factors work through a single cell signaling pathway T/F g) Signal transduction pathways regulate early development primarily through transcriptional mechanisms T/F e) The specific events that occur during an induction event are determined by the cell that secretes the signal. T/F f The ability of a cell to respond to an inductive event varies based on stage of development, location with the embryo and potentially many other circumstancesExplanation / Answer
1e) True. Both cells are similar in DNA, RNA and protein, suppose if one of the cells had already exposed to some extracellular ligand say X and due to the signalling cascade of this ligand makes changes such that signalling cascade of Ligand Y is affected by some modifying certain molecules and inactivating it (such as glucosylation) then both cells are exposed to ligand Y then cell which is pretreated will affect differently compared to untreated one. Case 2 when the ligand is binding to different receptors on cell and producing a different effects on both cells.
1f) False. a single growth factor can act on a cell through different signalling pathways. example: EGF epidermal growth factor can affect cell through many different pathways like MAP kinase pathway, AKT pathway.
1g) true. Signal transduction through Growth factors influences cell mainly by altering transcription.
2e) True. induction secretions of inducer cell affect responder cell.
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