Neisseria Meningitidis 1. Main biological features a. Cell shape, arrangement, G

Question

Neisseria Meningitidis

1. Main biological features

a. Cell shape, arrangement, Gram stain, endospores, capsule, unusual features.

2. Clinical Manifestations

a. List the diseases that are produced by this microorganism.

3. Mechanism of Disease

a. List of how the microorganism induces disease: Toxin, proteolysis, pyogenic, immunological mechanism or multiple mechanisms.

4. Transmission

a. How the microorganism is transmitted and who is at risk of acquiring the infection.

5. Prevention

a. List the most common prevention methods

b. Is there a vaccine?

6. Treatment

a. Is antimicrobial intervention necessary?

              b. Have resistant strains been detected?

c. List the common methods of treatment (you don’t need to list drug names).

d. Prognosis – Mortality associated with the disease

Explanation / Answer

Question 1 -

A - Cell shape - Double spherical shape, since two spherical shaped bacteria are involved.

Arrangement- Inner and outer membrane with a thin layer of peptidoglycan.

Gram stain - Gram-Negative

Endospore- Non-endospore forming bacteria.

Capsule- Meningococcal capsule

Unusual feature- Soft tissue involvement in children

Question 2 -

A- This bacteria can cause Meningitis and other forms of Meningococcal disease such as Meningococcemia, a life-threatening disease.

Question 3 - LOS is a component of the outer membrane of N.Meningitidis. This acts as an endotoxin and is responsible for septic shock and hemorrhage. Also, it infects the host cells by sticking to the pili.

Question 4 - It is spread by sharing respiratory and throat secretions ( like coughing, sneezing, etc.)

Question 5 - All the patients should receive medication. The agent of choice is generally - oral rifampium for a few days.

Yes, there is a vaccine for it called Meningococcal Vaccine.

Question 6-

A- Microbiologicak tests are suggested to be done.

C- Hospitalization, use of empirical treatment, use of Third-generation antibiotics.

D- The mortality risk if 15% withing 12 hours of receiving the infection

Related Questions

Navigate

• Browse (All)
• Browse N
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.