Which of the following statements about genomic DNA libraries are FALSE? (a) The

Question

Which of the following statements about genomic DNA libraries are FALSE?

(a) The larger the size of the fragments used to make the library, the fewer colonies you will have to examine to find a clone that hybridizes to your probe.
(b) The larger the size of the fragments used to make the library, the more difficult it will be to find your gene of interest once you have identified a clone that hybridizes to your probe.
(c) The larger the genome of the organism from which a library is derived, the larger the fragments inserted into the vector will tend to be.
(d) The smaller the gene you are seeking, the more likely it is that the gene will be found on a single clone.
(e) The shorter the oligonucleotide used to probe the library, the greater the number of colonies to which the probe will hybridize.

Explanation / Answer

(a) The larger the size of the fragments used to make the library, the fewer colonies you will have to examine to find a clone that hybridizes to your probe. this is false

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