1.9 Matching: Classify each of the following as a central/ primary or peripheral

Question

1.9 Matching: Classify each of the following as a central/ primary or peripheral/secondary lymphoid organ A. Bone marrow B. Lymph node C. Spleen D. Thymus E. Appendix 1.10 Matching: Match the following region, structure, or subcompartments with the numbered organ they are present in: A. Lymph node_ B. Spleen- C. Mucosa of the small intestine 1. Periarteriolar lymphatic sheath (PALS 2. Peyer's patches 3. High endothelial venules 1.11 Multiple Choice: Which of the following events do not occur during inflammation? A. Cytokine secretion B. Chemokine secretion C. Recruitment of innate immune cells D. Constriction of blood vessels 1.12 Fill-in-the-Blanks: nfected cells, while the immune system. T cells are able to kill T cells activate other cells of

Explanation / Answer

Que 1.9

Ans:

A. Bone marrow: central / primary lymphoid organ.

B. Lymph node: peripheral / secondary lymphoid organ.

C. Spleen: peripheral / secondary lymphoid organ.

D. Thymus: central / primary lymphoid organ.

E. Appendix: peripheral / secondary lymphoid organ.

Explanation:

- Lymphatic organs are generally divided into two categories: Primary (central) and Secondary (peripheral) lymphoid organs.

- The primary (central) lymphoid organs are those in which the maturation of T and B lymphocytes into antigen-recognizing lymphocytes occurs.

- Bone marrow and thymus are example of primary (central) lymphoid organs.

- The secondary (peripheral) lymphoid organs are those organs in which antigen-driven proliferation and differentiation takes place.

- The major secondary lymphoid organs are the spleen, the lymph nodes and mucosa associated lymphoid tissue (MALT).

Que 1.10

Ans:

A. Lymph node- High endothelial venules.

B. Spleen- Periarteriolar lymphatic sheath.

C. Mucosa of the small intestine- Peyer's patches.

Explanation:

- The lymph nodes are composed of medulla and cortex.

- The medullary area of lymph node contains antibody secreting plasma cells that have travelled from the cortex to the medulla via lymphatic vessels.

- The spleen is the largest of the secondary lymphoid organs.

- The interior of spleen consist of two compartments: Red pulp and White pulp.

- White pulp forms PALS (periarteriolar lymphoid sheath).

- Two major mucosa associated lymphoid tissue (MALT) includes bronchial associated lymphoid tissue (BALT) and gut associated lymphoid tissue (GALT).

- GALT includes the tonsils, adenoids and specialized region in the small intestine called Peyer's patches.

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