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Question: Useful links: https://www.pharmgkb.org/ http://www.ncbi.nlm.nih.gov/genome/ What can you find out...

Useful links:

https://www.pharmgkb.org/

http://www.ncbi.nlm.nih.gov/genome/

What can you find out about SNP: rs1136201

10)Does the rs1136201 SNP change the therapeutic response of the patient to treatment?

11)Does the rs1136201 SNP influence side effects, risks or adverse effect in patients?

12)Give the PMID of a paper to support your answer (reference)

13)Give the full citation of the journal article identified in (12)

Explanation / Answer

Ans10) The changes of the rs1136201 in the SNP makes the therapeutic response of the patients to treatment that they have shown low growth of the Human Epidermal receptor.When this done on the women breasts the results exhibited highly significant serum HER-2 elevation compared to those homozygous response of the systems.

Ans11)The side effects of the rs1136201 are the following:

1)Allelic imbalance in gene expression as a guide to cis-acting regulatory single nucleotide polymorphisms in cancer cells.

2)Interactions among genes in the ErbB-Neuregulin signalling network are associated with increased susceptibility to schizophrenia.

3)Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer.

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