The next 2 questions are applied. You should use information from your notes and

Question

The next 2 questions are applied. You should use information from your notes and apply it to answer the questions. Red blood cells tend to have a high fraction of saturated fats. In cells with a high fraction of saturated fats in the Oxygen will move more quickly than if there was a high fraction of unsaturated fats. Oxygen will move more slowly than if there was a high faction of unsaturated fats O Oxygen will move at the same rate, regardless of the membrane composition. QUESTION 10 n some cases of sickle cell disorders, G-PCRs are over-expressed leading to increased cell-signaling and increased sickling of cells. Which of the following might be a treatment for such disorders? O A non-hydrolyzable GTP analog OA dominant-negative receptor A molecule that constitutively blocks the ligand binding site An inhibitor of arrestin

Explanation / Answer

Ans

1)

A

Oxygen will move more faster if there is a high fraction of unsaturated fat in the red blood cells.

Unsaturated fats increase the solubility of oxygen in the blood and maintain fluidity of the RBC membrane.

Ans 10)

C

In treatment of sickle cell disorders, we would use a molecule that constitutively blocks tha ligand binding site.

This would prevent the over expression of G-PCRs and sickeling of red blood cells can be prevented.

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