The folowing is a typothetical pedigro for a famly some of whose membors have sy

Question

The folowing is a typothetical pedigro for a famly some of whose membors have symploms of Leigh syndrome, caused by an mDNA mutation that reducoes ATPase aciviby, Assume the mutation a fully penetrant ataxia (oss of motor function) P-peripheral neuropathy Which of the six individuals in the last generation would transmit the condition to their offispring? 0 aa ofthe women in the last gereration O all six individuals of the last generation O all of the women with the disorder all of the individuals with a mother that has the disorder allofthe inda uals with theda rder

Explanation / Answer

I believe the correct answer to be:

C) All the women with the disorder

due to the reason that mitochondrial DNA comes from the mother and only a female can transmit the disease to their offspring.

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