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tomy and Physiology Chapter 17 Part A Lecture: Blood 569 views Up next MacBook A

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Question

tomy and Physiology Chapter 17 Part A Lecture: Blood 569 views Up next MacBook Ai shn Ifa woman has type A bloot what donor blood typesansheulymcene dering.bloodtrand askin, Explain 11. 12. The resuts of a blood tyying test are shown bekow: What in the pernons blood typet Esplain Anti-A Anti B 13. In your textbook or on the Internet, research the condition called hemolytic disease of the newborn (HDN). Describe HDN and explain why it is important for a couple to know their blood types befoce having children. 370 EXERCISE 20 Blood Cells

Explanation / Answer

10. Neutrophils are the primary white blood cells that respond to a bacterial infection, so the most common cause of neutrophilia is a bacterial infection, especially pyogenic infections. Neutrophils are alsoincreased in any acute inflammation, so will be raised after a heart attack, other infarct or burns.

11. Blood group A individuals have the A antigen on the surface of their RBCs, and blood serum containing IgM antibodies against the B antigen. Therefore, a group A individual can receive blood only from individuals of groups A or O (with A being preferable).

12. People with type A blood have anti-B antibodies. People with type B blood have anti-A antibodies. Type O blood contains both types of antibodies. Blood group O is common, and individuals with thisblood type will have both anti-A and anti-B in their serum.

Blood typing is a method to tell what type of blood you have. Blood typing is done so you can safely donate your blood or receive a blood transfusion.

13. Hemolytic Disease of the Newborn (HDN), also known as erythroblastosis fetalis, isoimmunization, or blood group incompatibility, occurs when fetal red blood cells (RBCs), which possess an antigen that the mother lacks, cross the placenta into the maternal circulation, where they stimulate antibody production. The antibodies return to the fetal circulation and result in RBC destruction.

In an O-type mother, IgG ABO antibodies are produced and the baby can potentially develop ABO hemolytic disease of the newborn.  With maternal blood types A and B, isoimmunization does not occur because the naturally occurring antibodies (anti-A and -B) are IgM, not IgG. In type O mothers, the antibodies are predominantly IgG, cross the placenta and can cause hemolysis in the fetus. The association of a type A or B fetus with a type O mother occurs in ~15% of pregnancies. Therefore it is necessary to know the blood group for a couple before having children.