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Secreted proteins are enclosed in otein that reaches the TGN and has neither a l

ID: 135489 • Letter: S

Question


Secreted proteins are enclosed in otein that reaches the TGN and has neither a lysosomal tag, nor an ER retention signal will probably be 1.4. For the tagging of lysosomal proteins,the manose is phosphe 15. Secreted proteins are enclosed in vesicles in the TGN. g endocytosis, the membrane of the endocytie vesicle is derived from the plaima mmhis 17. Pinocytosis refers to the engulfment of uid manmo d 18. During phagocytosis, the cell xtends ps tulobd 19. Endocytic vesicles resulting from phagocytosis are called 20. During receptor-mediated endocytosis, membrane curvature and invagination is promoted by adaptor to surround the particle. protein and elathiny daranin 21. During receptor-mediated endocytosis, the separation of the formed vesicle from the plasma membrane is promoted by 22. During vesicle trafficking, the recognition between the vesicle and the target membrane is mediated and by 23. Worn-out organelles are digested after they have been enveloped into vacuoles. Part 2: Cytoskclctal system and cellular movements 24. In microtubules (MT), a single tack of tubulin dimer iscalled ap imut 25. The microtubules found in cili and aella are caled l ilami 26. The first step in microtubule formation is called huliohhy microtubules. during which dimers aggregate in oligomers? than the critical concentration 27. If the prevailing tubulin concentration is (CGl, the microtubules will grow

Explanation / Answer

14) for the tagging of lysosomal protein mannose is phosphorylated into mannose 6 phosphate. Mannose 6 phosphate is a key targeting signal for acid hydrolase precursor protein that are destined for transport to lysosome. Mannose 6 phosphate tag added to such proteind in golgi apparatus.

15) secretary proteins are enclosed in secretary granule or dense core vesicle in the trans golgi network. From this vesicle , protein secrete outside through exocytosis or desined to lysosome via late endosome.

21) during receptor mediated endocytosis, the separation of formed vesicle from plasma membrane is promoted by GTPase dynamin protein, it associated with neck of the budding vesicle and fuse the two lipid bilayer together in GTP dependent process, thereby cutting the neck and releasing the vesicle from the membrane.

22) during vesicle trafficking, the recognition between vesicle and target membrane is mediated by v SNARE and t SNARE. v SNARE bound to vesicle and t SNARE attached to target membrane.

23) worn-out organelles are digested after they have been enveloped into autophagic vacoule/ lysosome.

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