please answer all of the questions answering only one question is not helpful Qu

Question

please answer all of the questions answering only one question is not helpful

Question 2

Indicate whether each of the following occurs mainly in G1 phase (G), S phase (S), or G2 phase (H) of the cell cycle. Your answer would be a four-letter string composed of letters G, S, and H only, e.g. HGSS.
( )     DNA helicase activation
( )     DNA helicase deposition on DNA at the replication origins
( )     ORC phosphorylation
( )     Licensing of replication origins

SGSG

SSGG

GSGS

GGSS

SGGS

Question 6

Which of the following is more directly driven by active M-Cdk?

Centrosome maturation

Centrosome duplication

Nuclear envelope reassembly

Inactivation of APC/C

Cell cleavage

Question 7

In the fission yeast Schizosaccharomyces pombe, the proteins Cut1 and Cut2 form a complex that is catalytically inactive. At the onset of anaphase, Cut2 is polyubiquitylated by a large E3 complex containing Cut4, Cut9, Cut23, and other proteins, and is subsequently destroyed. Cut1 then cleaves Rad21, a non-SMC component of a complex that also contains two SMC proteins, thus allowing sister-chromatid separation. Mutations in the cut genes lead to the cut phenotype, in which the cell attempts cytokinesis without chromosome segregation. Indicate which of the following proteins or protein complexes corresponds to or contains the product of the genes cut1 (A), cut2 (B), cut4 (C), and rad21 (D). Your answer would be a four-letter string composed of letters A to D only, e.g. DCAB.

( )     Securin
( )     Cohesin
( )     Anaphase-promoting complex
( )     Separase

BDCA

CDBA

BCDA

ACDB

BDAC

Question 9

Indicate true (T) and false (F) statements below regarding mitosis and the changes that it brings about compared to interphase. Your answer would be a four-letter string composed of letters T and F only, e.g. TFTF.
( )     Microtubules become greatly stabilized in mitosis compared to interphase.
( )     The number of g-tubulin ring complexes in the centrosomes increases greatly during mitosis compared to interphase.
( )     Chromosomes stabilize mitotic microtubules through activation of Ran monomeric G protein.
( )     A bipolar spindle can be formed even in the absence of centrosomes.

FTTT

FFTT

TFTF  

TTFF  

FFFT

Question 10

Duplication of the centrioles is a highly regulated process that

requires proper tension be "measured" by the kineticore

does not occur in plants

requires modulation of the pericentriolar matrix

all of these answers

Explanation / Answer

Question 2:

Answer: SGSG.

Question 6

Answer: Nuclear reassembly.

Question 7:

Answer: BDCA

Question 9:

Answer: FFTT

During interphase, the centrosome regulates cell shape, motility and polarity, and the intracellular transport and positioning of organelles by organizing microtubules. During mitosis, the centrosome is located at the spindle pole and is involved in the formation of the bipolar spindle. Gamma tubulin are associated with polar orientation of microtubules, thus increased in interphase. (F)

Ran also known as GTP-binding nuclear protein

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