22. The resting membrane potential of a neuron =-73 mV. ECA+-+120 mV. The extrac

Question

22. The resting membrane potential of a neuron =-73 mV. ECA+-+120 mV. The extracellular concentration of calcium = 2 mM. The cytoplasmic concentration of calcium at the resting membrane potential-1 uM. In addition to calcium leak channels, the synaptic terminal of the neuron has voltage gated calcium channels in its membrane, which open in response to depolarization. In response to an action potential invading the synaptic terminal: a. calcium will leave the synaptic terminal b. a small number of calcium ions will enter the terminal through calcium leak channels c. a large amount of calcium ions will enter the synaptic terminal through voltage gated calciun channels d. calcium ions will be pumped out of the cell using a Ca2+ ATPase

Explanation / Answer

Option c.

This is so because the concentration increases from nearly less than 0.1 micrometer to nearly 1-100 micrometer.increased concentration of calcium allows it to bind to proteins(between synaptic vesicle and plasma membrane) leading to membrane fusion and consequently release of neurotransmitter.

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