1. Amino acid changes in the primary structure of the protein are not capable of
ID: 13320 • Letter: 1
Question
1. Amino acid changes in the primary structure of the protein are not capable of causing changes in theoverall shape of a protein.
a.) True
b.) False
2. An alpha helix:
a.) is destabilized by the amino acid alanine
b.) can only form by hydrogen bonding between different polypeptide chains
c.) can only form when cysteines form disulfide bridges within this structure
d.) all of the above
e.) none of the above
3. What will likely happen if two aspartates at pH 5 are next to each other in a polypeptide chain?
a.) The side chains of these amino acids will be uncharged and there will be no effect.
b.) The side chains of these amino acids will be charged and they will attract each other.
c.) The side chains of these amino acids will be charged and they will repel each other.
d.) Not enough information is given to determine the effect.
4. Consider the amino acid phenylalanine. Which of the following best describes where you predict this
amino acid would be found?
a.) This amino acid is hydrophobic and would be on the surface of a protein that is in the middle
of a membrane.
b.) This amino acid is hydrophilic and would be on the surface of a protein that is in the middle
of a membrane.
c.) This amino acid is hydrophobic and would be in the interior of a protein that is in the middle
of a membrane.
d.) This amino acid is hydrophilic and would be in the interior of a protein that is in the middle of
a membrane.
e.) Not enough information is given to determine.
5. The difference between fetal and adult hemoglobin with regard to oxygen binding occurs because fetal
hemoglobin has an amino acid substitution in one of its chains that results in a histidine being replaced by a
serine.
a.) True
b.) False
Explanation / Answer
1. Amino acid changes in the primary structure of the protein are not capable of causing changes in the overall shape of a protein.
(b) False. [it may effect the H-bonding which in turn effect the secondary and Tertiary structure]
2. An alpha helix:
a.) is destabilized by the amino acid alanine
3. What will likely happen if two aspartates at pH 5 are next to each other in a polypeptide chain?
c.) The side chains of these amino acids will be charged and they will repel each other.
4. Consider the amino acid phenylalanine. Which of the following best describes where you predict this
amino acid would be found?
e.) Not enough information is given to determine.
5. The difference between fetal and adult hemoglobin with regard to oxygen binding occurs because fetal
hemoglobin has an amino acid substitution in one of its chains that results in a histidine being replaced by a
serine.
(b) true [it is also called as scikkle cell anemia, it deform the 3D conformation of haemoglobin]
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.