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our ferite gene,you a ckisare test, it has 2 dgrees f freedom ond your p nalue i

ID: 132829 • Letter: O

Question

our ferite gene,you a ckisare test, it has 2 dgrees f freedom ond your p nalue i 0,05. You calealate that the X2 statitie i 6.3, what can you sag about your test? r A. ?0? hoee 8tatistically prooen that the null hypothesis is trae BYou filto rjeet the rallhypothesi r C. ?0ar obserration8 and gour expectation8 are different based on charce D You rejecthel ypohesis EC ond D Tronslatin con be wkiited bekedor repressed by NAs in cperation with RIS0 and Dicer How do m RNA's target spec c tr scripte? ?0ar (eswep ghould include a molecular mechnism

Explanation / Answer

1. Answer: Option E is correct

Explanation:

A small p-value (<0.05) indicates that the null hypothesis is rejected.

It means that the given expectation/observation cannot occur by a mere chance event.

2. Micro RNAs are small noncoding RNAs. Their size varies from 18-24 nucleotides.

They are produced by their own genes, unlike siRNA which are generated from the transcripts of other genes.

They bind to the target sequence with sequence complementarity. The binding can have two effects

i. Transcript degradation: Binding of miRNA recruits RISC complex which triggers the transcript degradation.

ii. Translation inhibition: Binding of miRNA can also recruit translation inhibition factors.

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