1. The mother produces antibodies from B cells that have become plasma cells. Ho
ID: 128183 • Letter: 1
Question
1. The mother produces antibodies from B cells that have become plasma cells. How is this accomplished? 2. The antibody from mother is transferred to the baby via breastmilk. The baby is born with only innate immunity. Describe the baby's innate immunity. 3. The antibody from mother then "primes" the baby's adaptive immune system. Which cell is receiving this antibody and what is done with adaptive immunity next? 4. T cells in the baby participate in the production of antibodies. Describe the system of MHC 11, peptide and T-cell receptor (TCR) in the three-different cell type that participate in antibody production. 5. CD8 Killer T cells and Natural Killer cells (NK cells) both have the ability to induce apoptosis in most cells of the body. What distinguishes these two cells and their killing abilities 6. Cancer is the result of the escape from the MHC-peptide/TCR surveillance system. Give an example.Explanation / Answer
1).
B lymphocytes are produced from the red bone marrow and are mainly involved in providing antibody-mediated immunity (or humoral immune response). When these cells encounter the presence of a specific antigen, they become activated or sensitized. In the subsequent processes, the antigens bound to the class II MHC proteins (major histocompatibility complex) present on B cell surface.
The same antigen also activates helper T cells; these T cells bind to the MHC of the activated B cell. This step helps in recognizing the antigen, and the helper T cells start secreting the cytokines that stimulate activation of B cells. This step helps in recognizing the antigen, and the helper T cells start secreting the cytokines that stimulate activation of B cells, and 1st exposure to antigen stimulate the production of memory B cells, which specifically attack certain antigens. Under the stimulation of cytokines, B cells differentiate into plasma cells that are capable of secreting antibody molecules about 100million per hour (per each plasma cell).
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