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Human albinos have no pigmentation in their skin, hair, or irises of the eyes. S

ID: 11955 • Letter: H

Question

Human albinos have no pigmentation in their skin, hair, or irises of the eyes.
Suppose that you gathered hospital records for the past 50 years for
normally pigmented couples who gave birth to one or more albino children. You
find that there were 70 normally pigmented babies and 17 albino babies born to
these couples. Use a chi-square test to determine if this pattern is a good fit to a
3:1 ratio (pigmented:albino), and explain your reasoning. (8 points) (You don't
have to show all of your calculations – just give the chi-square and P values, then
explain.)

Explanation / Answer

albinos have no pigmentation in their skin,-recessive tr ait    ---------------a

normal ------------A

Aa xAa

A

a

A

AA normal

Aa normal

                      a

aA normal

aa albinos

Ratio- 3:1

As every issue is independent event

Mendel’ law---------3:1------------law of dominance

chi-square test

Observed

expected

o-e

(o-e)^2

(o-e)^2/E

normal

70

65

5

25/65

0.38

albinos

17

22

-5

25/22

1.13

Total

87

87

1.51

chi-square test –VALUE----------1.51, IS LESS THAN TABLE VALUE AT 5% LEVEL OF SIGNIFICANCE

SO fit to a3:1 ratio

A

a

A

AA normal

Aa normal

                      a

aA normal

aa albinos

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