6. A 49-year-old woman was referred for a lipid evaluation by her dermatologist

Question

6. A 49-year-old woman was referred for a lipid evaluation by her dermatologist after she developed a papular rash over her trunk and arms. The rash consisted of multiple, red, raised lesions with yellow centers. She had no previous history of such a rash and no family history of lipid disorders or CHD. She is postmenopausal, on standard estrogen replacement therapy, and otherwise healthy (see lab results to the right). Laboratory Results Serum Triglycerides Total cholesterol Fasting glucose Grossly Lipemic 6,200 mg/dL 458 mg/dl 160 mg/dl Normal Liver function tests and electrolytes a. What is the rash? What is the cause of her rash? b. Is her oral estrogen contributing? c. Is her glucose contributing? d. What is her most acute risk?

Explanation / Answer

a)

The rash is due to her hypertrigcerides.

b)

yes, women usually get high triglycerides with oral oestrogen treatment as oestrogen causes papular rashes .

c)

no. but she has to worked up for Dibetes Mellitus and to start on drugs

d)

she has acute risk of developing acute pancreatitis and can present with sudden onset of abdominal pain

she has to be put on lipid lowereing agents to reduce her triglycerides.

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