Not Set 4 83.9/100 1/22/2018 08:33 PM Gradebook Print Calculator Ed Periodic Tab

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Not Set 4 83.9/100 1/22/2018 08:33 PM Gradebook Print Calculator Ed Periodic Table Question 28 of 32 Determine how feedback inhibition of enzyme 1 by a high concentration of product Z affects the concentrations of the different substrates for the following reaction pathway. Assume that product Z diffuses out of the cell enzyme 1 enzyme 2 enzyme 3 The concentration of X Select answer The concentration of Y Select answer The concentration of Z Select answer What happens if the concentration of Z decreases? O Enzyme 3 regains its shape. O Enzyme 1 becomes inactive. O Enzyme 2 activity stops O Enzyme 1 activity increases O Previous ® Give Up & View Solution e, Check Answer 0 Next Exit 9 Hint

Explanation / Answer

Ans. Given,

            Product Z inhibits enzyme 1 through feedback inhibition.

# In the concentration of Z decreases – D. Enzyme 1 activity increases.

Since Z inhibits enzyme 1, lowering [Z] or removing the inhibitor from reaction mixture or cytoplasm with cause an increase in activity of enzyme 1.

Since NO correlation other than “Product Z inhibits enzyme 1 through feedback inhibition” has been mentioned, option D is the correct option.

# Option A. Incorrect. No direct correlation can be made. Since Z does not inhibit enzyme 3, lowering [Z] shall not induce conformational change in enzyme 3

Option B. Incorrect. See #D

#C. No direct correlation can be made.

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