Map Sapling Learning macmillan learning A variety of factors influence enzyme ac
ID: 1031895 • Letter: M
Question
Map Sapling Learning macmillan learning A variety of factors influence enzyme activity. Substances that bind to the enzyme and interfere with substrate binding or catalysis are inhibitors. Identify the type of inhibition associated with each of the following descriptions and examples by sorting each item into the appropriate bin Irreversible inhibition Competitive inhibition Mixed inhibition te: If you answer this question incorrectly, a single red X will appear indicating that one or more of the phrases are sorted incorrectly inhibitor may permanentlya transition state analog the Aljt ion binds to acetylcholinesterase or to the acetylcholinesterase-substrate complex modify an enzyme binds reversibly to isomerase binding by the binding by the inhibitor inhibitor increases Km but decreases Vmax increases Km, but not Vmax DIPF permanently modifies the hydroxyl group of a Ser residue at the active siteExplanation / Answer
1) The Al3+ ion binds to acetylcholinesterase or to the acetylcholinesterase- substrate complex .........this is mixed inhibition .
2) Inhibitor may permanently modify an enzyme..........this is irreversible inhibition.
3) a transition state analog binds reversiblyto isomerase.......... This is competitive inhibition.
4) Binding by the inhibitor increases Km but not Vmax ......... This is competitive inhibition.
5) Binding by the inhibitor increases Km but decreases Vmax ........... This is mixed inhibition
6) DIPF permanently modifies the hydroxyl group of a Ser residue at the active site.......... This is irreversible inhibition.
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