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2. The final form of mRNA in eukaryotes has all these features, exeept a. There

ID: 100728 • Letter: 2

Question

2. The final form of mRNA in eukaryotes has all these features, exeept a. There will be a special nucleotide cap on the 5" end of the mRNA. b. There is usually a poly A tail on the 3' end of the mRNA. c. The mature, active mRNA contains introns. d. Only a single protein is made from any mature mRNA molecule. e. All of these are true. 3. Inosine or hypoxanthine can wobble with all the following bases, exeept: a. A b. C c. T d. U e. Inosine can wobble with all of these bases. 4. In the wobble phenomenon, the base that wobbles is found in a. the tRNA. b. the mRNA c. either the tRNA or the mRNA. 5. What type of assay using tRNAs and ribosomes enabled complete determination of th a. filter binding assays b. high performance chromatography c. electrophoresis d. density gradient centrifugation 6. Ribosomal frameshifting in Influenza Virus A is caused by the fact that a. the virus has a modified genetic code b. the virus attacks the mRNA c. the ribosome races a mae rginine codon and sal o d. none of these Cengage Le

Explanation / Answer

Answer:

6). A. The viruw has a modifies genetic code

Ribosomal frameshifting used in influenza A virus expression occurs within the sequence UCC_UUU_CGU and is in the +1 direction.

7). B. It allows for making more than one protein from the same coding sequence

8). A. Endoplasmic reticulum

9). B. “P” site of the ribosome

The first or intiatior, tRNA molecule, bearing the modified amino acid fMet, binds to the AUG initiation codon on the mRNA. The large ribosomal subunit locks into place, with the tRNA occupying the P(peptidyl) site. The A(aminoacl) and E (exit) sites are vacant.

10). A. “A” site of the ribosome

During translocation and elongation, the ribosome moves one codon 3' down the mRNA, brings in a charged tRNA to the A site, transfers the growing polypeptide chain from the P-site tRNA to the carboxyl group of the A-site amino acid, and ejects the uncharged tRNA at the E site.

11). A. Puromycine

Puromycin is an antibiotic that is a protein synthesis inhibitor by inhibiting translation. Causes premature chain termination during translation taking place in the ribosome.

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