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5) Cells become cancerous after mutations accumulate in the various genes that c

ID: 100490 • Letter: 5

Question

5) Cells become cancerous after mutations accumulate in the various genes that control cell production. According to research findings from the Cancer Genome Project, most cancer cells possess 60 or more mutations. The challenge for medical researchers is to identify which of these mutations are responsible for particular kinds of cancer. Should a person be concerned about cancer arising from cells in the stratum granulosum which is a layer of the epidermis?

A) No, the person should not be concerned. The epidermis consists of five layers. The first layer from inside (stratum basale) is the only layer that divides to form new cells. Stratum granulosum is the third layer from inside. Cells in this layer do not divide, they are mostly keratinized. If a cancer cell arises at this level, the cell will not be able to divide and increase the number of cancer cells. Eventually, this cell will move up in the layers of the epidermis; it will die and be replaced by new cells.

B) A person should not be concerned of cancer in the stratum granulosum since the cancer is not deep in the stratum basale so it cannot get into the bloodstream and proliferate and spread. A cancer in the higher levels of skin layers can be taken out with incisions and are usually treatable and curable if caught in time.

C)Yes, a person should be concerned about cancer cells arising in the stratum granulosum because it has thin bilayers, making it easy for cells that are able to pass through. Also, skin cancer is a cancer that usually has cancer cells that arise in the stratum granulosum.

Explanation / Answer

A) No, the person should not be concerned. The epidermis consists of five layers. The first layer from inside (stratum basale) is the only layer that divides to form new cells . Stratum granulosum is the third layer from inside. Cells in this layer do not divide, they are mostly keratinized. Ifa a cancer cell arises at this level, the cell will not be able to divide and increase the number of cancer cells . Eventually , the cell will move up in the layers of the epidermis; it will die and be replaced by new cells. that statement is correct.

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