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You synthesized a hydrogel composite with liposomes that produced the following

ID: 996372 • Letter: Y

Question

You synthesized a hydrogel composite with liposomes that produced the following release curves at 37, 41 and 45°C. Which of the statements could be true?

A. The liposomes used were made out of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), which melts at 41°C, accounting for the increase in release rate between 37 and 45°C.

B. The data likely follows the power law model at the three temperatures.

C. The low permeability of liposomes could account for the flat release profile at 37°C.

D. None of the above

55°C 45 37 C Time

Explanation / Answer

B. The data likely follows the power law model at the three temperatures.

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