Use the following diagram from a Nature Review article that outlines +RNA viral

Question

Use the following diagram from a Nature Review article that outlines +RNA viral replication to help you answer the activity questions on the next page.

9. How could you be assured that this new antiviral medication you developed would not be harmful to the patient?

Receptor binding Pro-apoptotic Anti-apoptotic effects effects Entry Shut off host cell (cap- dependent) translation Shut off host cell transcription Polyprotein st Interactions between the virus and the cell cycle Uncoating Viral replication complex Negative strand synthesis 5 dsRNA (latency?) IRES-driven translation strand (genome) 5 3 3' 3' 3 5 Packaging Cell lysis Viral egress

Explanation / Answer

Ans- the medicine is harmful for patient or not will be assured on the fact- if it is causing Lysis of viral cells but no Lysis of host cells then it is unharmful but if it causes Lysis of host cells along with viral cells then it will be considered as harmful. Or if it has some other types of side effects then also it will be considered as harmful.

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