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Genetic testing is being done for a large number of genetic diseases that have a

ID: 97046 • Letter: G

Question

Genetic testing is being done for a large number of genetic diseases that have a Mendelian, i.e. single-gene, pattern of inheritance. It has been very successful at predicting the risk of rare genetic diseases. There are some traits that are medically significant such as hypertension which are multifactorial in nature. Their genetics is understood by the principles of quantitative genetics. There has been progress in identifying genes that are involved in variation in these traits, but it is not recommended that genetic testing be offered for these traits. Provide and explain one reason why genetic testing is not appropriate to use genetic testing to predict whether someone will develop hypertension later in life, even though genetic testing has been very successful at predicting people's risks of developing Mendelian genetic disease

Explanation / Answer

Genetic disease is present in gametes before conception and can be detected by using variety of technologies including biochemical or DNA based techniques.

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