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A change in gene expression is a common output of a given cell signaling pathway

ID: 97025 • Letter: A

Question

A change in gene expression is a common output of a given cell signaling pathway. Many transcription factors have been mentioned throughout this course that are activated in response to various forms of stress. Match each transcription factor with its correct description/role.

1. HIF 1 beta

      [ Choose ] a.DNA damage response b. Oxidative Stress c. unfolded protein response d. hypoxia response e. gluconeogenesis f. autophagy machinery genes g. G1 arrest h. lipid uptake/storage      

2. Nrf1

      [ Choose ]            DNA damage response            Oxidative Stress            unfolded protein response            hypoxia response            gluconeogenesis            autophagy machinery genes            G1 arrest            lipid uptake/storage      

3. ATF4

      [ Choose ]            DNA damage response            Oxidative Stress            unfolded protein response            hypoxia response            gluconeogenesis            autophagy machinery genes            G1 arrest            lipid uptake/storage      

4. p53

      [ Choose ]            DNA damage response            Oxidative Stress            unfolded protein response            hypoxia response            gluconeogenesis            autophagy machinery genes            G1 arrest            lipid uptake/storage      

5. p21

      [ Choose ]            DNA damage response            Oxidative Stress            unfolded protein response            hypoxia response            gluconeogenesis            autophagy machinery genes            G1 arrest            lipid uptake/storage      

6. CHOP

      [ Choose ]            DNA damage response            Oxidative Stress            unfolded protein response            hypoxia response            gluconeogenesis            autophagy machinery genes            G1 arrest            lipid uptake/storage      

7. FOXO1

      [ Choose ]            DNA damage response            Oxidative Stress            unfolded protein response            hypoxia response            gluconeogenesis            autophagy machinery genes            G1 arrest            lipid uptake/storage      

8. PPAR gamma

  [ Choose ]            DNA damage response            Oxidative Stress            unfolded protein response            hypoxia response            gluconeogenesis            autophagy machinery genes            G1 arrest            lipid uptake/storage    

Each one is correct for each option. Please help me as soon as possible. Thanks

Explanation / Answer

1. HIF 1 - d.Hypoxia response

2. Nrf1 - b.Oxidative Stress

3. ATF4 - f.autophagy machinery genes

4. p53 - a.DNA damage response

5. p21 - g.G1 arrest

6. CHOP - c.unfolded protein response

7. FOXO 1- e.gluconeogenesis

8. PPAR gamma - h.lipid uptake/storage

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