Academic Integrity: tutoring, explanations, and feedback — we don’t complete graded work or submit on a student’s behalf.

please provide an explanation if you can, thanks! A 22-year-old female works in

ID: 96857 • Letter: P

Question

please provide an explanation if you can, thanks!

A 22-year-old female works in a chimpanzee lab and is studying a virus called SIV that appears to destroy entire populations of primate CD4+ T-cells. Working late one night, she accidentally incubates the virus with a culture of human CD4+ T-cells infected with a different, non-pathogenic virus. During the viral replication process, some of the SIV RNA is exchanged with that of the virus capable of infecting human immune cells. The accident resulted in: A. Viral affinity maturation B. Antigenic shift C. Somatic recombination D. Antigenic drift E. Original antigenic sin

Explanation / Answer

Answer: (B) Antigenic shift

Explanation:

When one of the genes or RNA strands is substituted with a gene or strand from another virus from a different animal host, it is called antigenic shift. It results in a new sub type with a mixture of antigenic combinations from the two original strains.

Here, the SIV RNA gets exchaged with the virus capable of infecting human immune cells, thus resulting in antigenic shift.