A DNA binding protein recognizes a specific 8 nucleotide sequence in DNA. Assumi

Question

A DNA binding protein recognizes a specific 8 nucleotide sequence in DNA. Assuming that the binding is perfectly specific, how many binding sites are expected to exist for it in human genomic DNA, which is composed of about 6 x 10^9 nucleotide pairs? What about if the protein forms a homodimer? Note that the target sequence can be oriented either way in the double stranded DNA

Explanation / Answer

Correct answer is :

e) About 200,000; about 3

Expected binding sites in the DNA is 200,000

When homodimer is formed the number of binding sites are 3

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