Substitution of bromine by t-butyl amine is the second step of the reaction toda

Question

Substitution of bromine by t-butyl amine is the second step of the reaction today. Secondary alkyl halides can undergo substitution by Sn1 or Sn2 mechanisms. Explain (in terms of electronic interactions) why an Sn2 mechanism may be more favored in this case when the bromide is alpha to a carbonyl. Based on your answer in 3. select the most likely reaction pathway and explain how' the substitution mechanism forms the product structure(s) shown. The 2M HCl solution is made by mixing acetyl chloride with isopropyl alcohol. Calculate the volume of 2M HCI in millliters that would be required to protonate the Zyban analog assuming 100% of theoretical yield.

Explanation / Answer

molarity = given weight * 1000 / ( molecular weight * volume)

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