Lung cancer is deemed by experts to be a terminal illness. The survival rates ma

Question

Lung cancer is deemed by experts to be a terminal illness. The survival rates may be influenced by treatment or supportive care. The following graph illustrates these survival rates: How can the survival curve be used to show treatment response?

A) Evaluate effectiveness of treatment over time

B) Evaluate effectiveness of treatment over medications

C) Differentiate ineffectiveness by treatment type

100 Supportive care plus chemotherapy Supportive care 80 701 60 50 20 10 No at risk Supportive care 12 18 24 Time from randomisation (months) 98 219 125 47 28 28 16 Supportive care 362

Explanation / Answer

The survival curve gives an indication of how effective is the treatment strategy over a period of time. The number of people surviving over a period of time indicates the effectiveness of the treatment, while less number of individuals surviving over a period of time indicates ineffectiveness of the treatment.

In the above graph, the supportive care plus chemotherapy seems to be effective over only supportive care as the percentage survival are more at all time points analyzed. The survival curves can be used to show the effectiveness of treatment over time.

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