Which of the following might occur as a direct result if the basement membrane b

Question

Which of the following might occur as a direct result if the basement membrane between the glomerular endothelial cells and Bowman's capsule was removed? A. Increase filtrate production B. Decrease amount of waste products filtered C. Abnormally high protein concentration in the urine D. B and C E. A and C Efferent arteriolar vasoconstriction causes the glomerular-capillary blood pressure to ______ leading to a(an) ______ in the net filtration pressure and a resultant ______ in the glomerular filtration rate. A. Increase: increase: increase B. Decrease: decrease: decrease C. Increase: decrease: decrease D. Decrease: increase: increase

Explanation / Answer

20.Ans- D

Basement membrane is the portion between the endothelium which is closer to the Blood capillary and epithelium that lined with podocytes. Basement membrane limits the passage of proteins like albumin etc.Due to increase more proteins and other electrolytes would exit the glomerulus and flow into the renal tubules and as result filtrate production increase. When filtration membrane which form by two epithelia and the basement membrane is not functioning properly that stops to act like an effective barrier and then occurs is proteinuria, an abnormal accumulation of protein in the urine

21. Ans- D

Vasconstriction of the efferent arteriole decreases blood pressure of the glomerulus and thus blood flow is decreases and this increases the glomerular hydrostatic pressure and leads to an increase in GFR.

Constriction of the afferent arteriole decreases the blood pressure of the glomerulus and this decreases glomerular hydrostatic pressure which leads to a decrease in GFR.

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