4. In medicinal chemistry LogP stands for a. Logarithm of the octanol-water fric

Question

4. In medicinal chemistry LogP stands for a. Logarithm of the octanol-water friction coefficient b. Logarithm of the octanol-water partition coefficient c. Logarithm of the chloroform-water partition coefficient d. Logarithm of the petroleum ether-water partition coefficient e·Logarithm of the benzene-water partition coefficient 5. Atorvastatin (Lipitor), the top selling marketed drug, is a derivative of Atorvastatin (Lipitor) a. pyrrole b. indole c. thiophene d. imidazole e, none of the above 6. Distomer is the which demonstrates therapeutic activity. a. enantiomer, most c. regioisomer, most d. enantiomer, least e. polymer, least 7. How many stereocenters are present in cholesterol

Explanation / Answer

5. Atorvastatin is a derivative of pyrrole

6. A distomer is the enantiomer of a chiral compound that is the less potent for a particular action.

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