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choose two out of 10 essay question to answer Prepare 2 o 10 questions to 1. Des

ID: 94311 • Letter: C

Question


choose two out of 10 essay question to answer

Prepare 2 o 10 questions to 1. Descri IVE microbial VIRULENCE FACTORS and provide at example for each of them least one microbe 2. What is the relationship between Gram staining and choice of antibiotics? Explain 3. Provide and explain THREE justifications to convince a mother to let her baby get all necessary vaccine shots 4. Enumerate 4 SHARED ways of transmission and 4 SHARED ways of prevention of the following pathogens: HIV and Hepatitis B virus 5. Name THREE common microbial agents of pneumonia, at least THREE common symptoms and give THREE examples of tests that may help distinguish between these THREE microbes 6. What are 3 different characteristics or facts shared in common by the following bacteria in common? Neisseria meningitidis Haemophilus influenzae, Streptococcus pneuoniae? Explain 7. Name THREE microbes that have been linked or have the potential to cause pandemics and at least one reason of your choice for eaclh microbe 8. What is one thing all hepatitis share? What is one thing different in all hepatitis? Provide THREE specific way to prevent hepatitis A and THREE specific way to prevent hepatitis C 9. What are TWO concerms with diseases like Haemophilus influenzae meningitis and whooping cough if there are vaccines available to prevent them? Explain 10. Name FIVE microbes with multiple (at least TWO) FREQUENT ways of n and which those ways are

Explanation / Answer

10.HIV- blood,semen and saliva.

Bacillus anthraci-air

Vibrio cholerae-water

Staphylococcus aureus,Clostridium botulinum-food

Plasmodium vivax-mosquitoes

Yersina pestis-rat flea

1.VIRULENCE FACTORS

(a)Adhesion-its the ability of a bacteria to adhere to host cell and resist physical removal by using pili,adhesins and glycocalyx.eg:E.Coli using fimbriae for adhesion to host.

(b)Invasion-ability to enter,multiply and spread in host.Eg:salmonella, a bacterium found in contaminated raw foods thrives in the digestive tract despite the immune system's best efforts to destroy it.

(c)Resistance- ability to resist host immunity or prevent phagocytosis by host by forming defensive mechanism such as capsules.eg:Neisseria meningitidis

(d)Secretion of endo/exotoxins- This is used by the microbe to destroy host tissues.eg:Diphtheria toxin by Corynebacterium diphtheriae inhibits protein synthesis in eukaryotic cells.

(e)competition for iron and nutrients- Bacteria produces siderophores which in turn bind iron necessary for host.eg:the anthrax pathogen Bacillus anthracis releases two siderophores, bacillibactin and petrobactin, to scavenge ferric iron from iron proteins.