Susan is a 25 year old top notch executive in a small Midwestern insurance compa
ID: 93652 • Letter: S
Question
Susan is a 25 year old top notch executive in a small Midwestern insurance company. She recently applied to a much larger national insurance firm whose home office is in Milwaukee Wisconsin. The location is ideal since she can commute to work and her husband can keep his current job. They have no children but plan to have some in the near future. The benefits for the new firm are much better than in her current job as is the salary and prestige. She has had a first interview that went very well. The new firm does require each new employee undergo a medical exam which includes drug and genetic testing. This is the hitch for Susan since her mother was recently diagnosed with Huntington's Disease. List all possible genotypes for Susan's mother. Based on each of the possible genotypes you listed for Susan's mother, what are the chances Susan will inherit Huntington's Disease? List the probability of Susan inheriting Huntington's for each possible genotype for Susan's mother. What is the prognosis for Susan's mother? If you were Susan would you want to know you were going to develop Huntington's? Why would you want to know or not want to know? If you were Susan would you want your husband to know you were going to develop Huntington's? Why or why not? Should husband or why her know? Why or why not? Can the insurance company refuse to hire her based on the health exam results? Why would the benefit's administrator (usually in the human resources or HR department) want to know this information? What potential impact would hiring Susan have on the other employees of the new firm? Separate groups: BIO-111-950-2017SUExplanation / Answer
1) Huntington's disease is inherited in an autosomal dominant fashion. So, the possible genotypes in Susan's mother who was diagnosed with Huntington's disease iare,
2) When Susan's mother has HH genotype, there is 100 % chance that Susan will get affected. if the genotype of Susan's mother is Hh, Susan has 50% chance of being affected with the disease.
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